The talk is by Dr. Randy Pausch in 1997 and I wish I had seen it when I was a grad student.
If you haven’t run across Dr. Pausch yet through email, or through the media or browsing Wikipedia yet, you may want to get to know him through his lectures and his projects. He’s helped a lot of people in his life, and by extension many more without realizing it was going to happen that way. He’s someone to listen to, if only that he’s naturally earnest and intelligent, and to paraphrase him in the Time Management talk, “experience is valuable”.
For those who want a shortcut, you can find his famous and fabulous CMU lecture here at Google Video